Feature: for medium temperatures > °C or frequent changes in temperature. 0 to 1 bar – 0 to 60 bar relative, 0 to 1 bar – 0 to 25 bar absolute; Medium. HART® interface; Optional explosion protection [Ex ia] according to ATEX, GOST- R, DNV; Linearity %; Turn down: ; Simple operation with rotary knob. Get this from a library! Farmacevtska tehnologija. Del 1, Praktikum. [Julijana Kristl ; Jelka Šmid-Korbar; Stanko Srčič].
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URL – Presentation file, Visit http: Granule shape was affected by interplay of binder content, binder particle size and granulation time. Voting is allowed only to logged in users.
The effect of the Wurster gap and fluidizing air flow rate on gas-solidflow was analyzed in both simulations and experiments. The results of the present study indicate that fluidized hot melt granulation is a promising powder agglomeration technique for spherical granules production.
Farmacevtska tehnologija: Praktikum. Del 1
A rather good agreement between the simulated and experimental results was observed and thus it can be assumeed that this particular simulation setup represents a computationally reasonable tool that provides a valuable farmacdvtska into the Wurster coating process due to the impact of two-phase flow properties on the process.
Granule size was mainly influenced by binder particle size.
The results obtained indicate that conventional fluid bedgranulator may be suitable for production of highly spherical agglomerates,particularly when immersion and layering farmacevstka dominant agglomeration mechanism.
Hydrophilic polyetilenglycol and hydrophobic meltable binder glyceryl palmitostearate were used for in situ fluidized hot melt granulation.
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Experimentally, the draft tube two-phase flow was evaluated by measuring the volume fraction of pellets within the draft tube and local particle velocities at the tube exit and by monitoring the local pressure drop fluctuations. You have to log in to leave a comment. URL – Presentation file, Visit http: You have to log in to leave a comment. The aim of this study was to investigate the influence of binder content, binder particle size, granulation time and inlet air flow rate on granule sizeand size distribution, granule shape and flowability, as well as on drug release rate.